The PRKACB Polyclonal Antibody (CAB5324) is specifically designed for research involving PRKACB, a protein kinase that plays a critical role in various cellular processes. The antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds specifically to the PRKACB protein, allowing for detection and analysis in a variety of cell types, making it an ideal tool for studies in cell signaling and cancer research.PRKACB is involved in the regulation of numerous cellular functions, including metabolism, cell growth, and gene expression. Dysregulation of PRKACB has been implicated in various diseases, making it a potential target for therapeutic intervention.
Understanding the role of PRKACB in cell signaling pathways is essential for developing treatments for conditions such as cancer, diabetes, and cardiovascular disease.Overall, the PRKACB Polyclonal Antibody (CAB5324) is a valuable tool for researchers studying the function and regulation of PRKACB in cellular processes and disease states. Its high reactivity and specificity make it a reliable choice for Western blot analysis, leading to further insights into the role of PRKACB in health and disease.
Product Name:
PRKACB Rabbit Polyclonal Antibody
SKU:
CAB5324
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-351 of human PKA C-beta (PRKACB) (NP_002722.1).
The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
5567
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat spleen, using PKA C-beta (PRKACB) Rabbit pAb (CAB5324) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
