The PRKACB Polyclonal Antibody (CAB15709) is a valuable tool for researchers studying PRKACB, a protein kinase involved in various cellular processes, including cell growth and differentiation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the PRKACB protein, this antibody enables the detection and analysis of PRKACB in different cell types, making it an essential asset for research in cell biology and cancer studies.
PRKACB, also known as protein kinase A catalytic subunit beta, plays a crucial role in signal transduction pathways that regulate cell proliferation and survival. Dysregulation of PRKACB has been associated with various diseases, including cancer and metabolic disorders, making it a promising target for therapeutic interventions. Understanding the function of PRKACB is essential for developing treatments that target this kinase and its downstream signaling pathways in disease states.
Product Name:
PRKACB Rabbit Polyclonal Antibody
SKU:
CAB15709
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human PKA C-beta (PRKACB) (NP_002722.1).
The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
5567
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PKA C-beta (PRKACB) Rabbit pAb (CAB15709) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
