AMPKα1 Rabbit Polyclonal Antibody (CAB16960)
- SKU:
- CAB16960
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | AMPKα1 Rabbit Polyclonal Antibody |
SKU: | CAB16960 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 421-520 of human AMPKα1 (NP_006242.5). |
Sequence: | MAEV CRAI KQLD YEWK VVNP YYLR VRRK NPVT STYS KMSL QLYQ VDSR TYLL DFRS IDDE ITEA KSGT ATPQ RSGS VSNY RSCQ RSDS DAEA QGKS SEVS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | AMPK; AMPKa1; AMPK alpha 1; AMPKα1 |
Positive Sample: | HeLa,293T,MCF7,NIH/3T3,mouse brain |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 64kDa |
Observed MW: | 64kDa |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 5562 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |