The Prickle4 Antibody (PACO35886) is a crucial tool for research involving the Prickle4 protein, which plays a significant role in cell polarity and development. This polyclonal antibody, produced in rabbits, is highly specific and reactive to human samples, making it an excellent choice for Western blot applications. By targeting the Prickle4 protein, this antibody allows for the detection and analysis of this essential molecule in various cell types.Prickle4 is known for its involvement in planar cell polarity and ciliogenesis, making it a key player in the development and organization of tissues and organs. Research into Prickle4 is essential for understanding how cells establish and maintain their orientation within tissues, which is critical for proper physiological function.
This antibody is an invaluable tool for studying Prickle4's function in developmental biology, neurobiology, and other related fields.By utilizing the Prickle4 Antibody (PACO35886), researchers can gain insights into the molecular mechanisms underlying cell polarity and development, paving the way for potential therapeutic interventions targeting Prickle4-related pathways. Studies using this antibody have the potential to advance our understanding of tissue organization and disease pathogenesis, making it a valuable asset for researchers in various scientific disciplines.
Antibody Name:
PRICKLE4 Antibody (PACO35886)
Antibody SKU:
PACO35886
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Prickle-like protein 4 protein (1-240AA)
Immunohistochemistry of paraffin-embedded human liver cancer using PACO35886 at dilution of 1:100.
Synonyms:
Prickle-like protein 4 (Overexpressed breast tumor protein), PRICKLE4, C6orf49 OEBT
UniProt Protein Function:
PRICKLE4: Belongs to the prickle / espinas / testin family. 3 isoforms of the human protein are produced by alternative splicingChromosomal Location of Human Ortholog: 6p21.31Cellular Component: nucleusMolecular Function: zinc ion binding
UniProt Protein Details:
NCBI Summary:
C6ORF49 is a member of the LIM domain protein family (Teufel et al., 2005 [PubMed 15702247]).[supplied by OMIM, Mar 2008]
