PRG2 Rabbit Polyclonal Antibody (CAB2532)
- SKU:
- CAB2532
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
Product Name: | PRG2 Rabbit Polyclonal Antibody |
SKU: | CAB2532 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human PRG2 (NP_002719.3). |
Sequence: | GIPG CQTC RYLL VRSL QTFS QAWF TCRR CYRG NLVS IHNF NINY RIQC SVSA LNQG QVWI GGRI TGSG RCRR FQWV DGSR WNFA YWAA HQPW SRGG HCVA L |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | MBP; BMPG; MBP1; proMBP; PRG2 |
Positive Sample: | Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic vesicle, Secreted, secretory vesicle. |
Calculated MW: | 25kDa |
Observed MW: | 33kDa |
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5553 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |