The PrePL Polyclonal Antibody (CAB14348) is a powerful tool for researchers studying PrePL, a protein involved in the regulation of immune responses. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PrePL protein, this antibody facilitates the detection and analysis of PrePL in a variety of cell types, making it a valuable asset for studies in immunology and cancer research.PrePL, also known as immune modulator, plays a crucial role in maintaining immune balance by regulating inflammatory processes and modulating immune responses.
Its involvement in immune function modulation highlights its importance as a target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. A comprehensive understanding of the role of PrePL is essential for the development of therapeutic interventions aimed at manipulating immune responses in these disease states.
Product Name:
PREPL Rabbit Polyclonal Antibody
SKU:
CAB14348
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 578-727 of human PREPL (NP_006027.2).
The protein encoded by this gene belongs to the prolyl oligopeptidase subfamily of serine peptidases. Mutations in this gene have been associated with hypotonia-cystinuria syndrome, also known as the 2p21 deletion syndrome. Several alternatively spliced transcript variants encoding either the same or different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
9581
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PREPL Rabbit pAb (CAB14348) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.