PRELP Rabbit Polyclonal Antibody (CAB18573)
- SKU:
- CAB18573
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PRELP Rabbit Polyclonal Antibody |
SKU: | CAB18573 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human PRELP (NP_002716.1). |
Sequence: | LDLQ HNRL SDGV FKPD TFHG LKNL MQLN LAHN ILRK MPPR VPTA IHQL YLDS NKIE TIPN GYFK SFPN LAFI RLNY NKLT DRGL PKNS FNIS NLLV LHLS HNRI SSVP AINN RLEH LYLN NNSI EKIN GTQI CPND LVAF HDFS SDLE NVPH LRYL RLDG N |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MST161; SLRR2A; MSTP161; PRELP |
Positive Sample: | Mouse lung,Rat heart |
Cellular Localization: | extracellular exosome, extracellular region, extracellular space, extracellular vesicle, Golgi lumen, lysosomal lumen |
Calculated MW: | 44kDa |
Observed MW: | 44kDa |
The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
Purification Method: | Affinity purification |
Gene ID: | 5549 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |