The Prefoldin Subunit 2 Polyclonal Antibody (CAB12269) is a valuable tool for researchers studying the Prefoldin protein complex and its role in protein folding and chaperone activity. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Prefoldin Subunit 2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in cell biology, molecular biology, and protein research.Prefoldin Subunit 2 is an essential component of the Prefoldin complex, which assists in the proper folding of newly synthesized proteins and aids in their transport to the chaperonin for further folding.
Understanding the function and regulation of Prefoldin Subunit 2 is crucial for unraveling the mechanisms of protein folding and maintaining proteostasis within cells. Research using this antibody can provide valuable insights into the role of Prefoldin Subunit 2 in cellular processes and its potential implications in diseases related to protein misfolding and aggregation.
Product Name:
PFDN2 Rabbit Polyclonal Antibody
SKU:
CAB12269
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human PFDN2 (NP_036526.2).
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
Purification Method:
Affinity purification
Gene ID:
5202
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PFDN2 Rabbit pAb (CAB12269) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
