The KO Validated Peroxiredoxin 4 Polyclonal Antibody (CAB1486) is a valuable tool for researchers studying Peroxiredoxin 4, an important antioxidant enzyme that plays a key role in protecting cells from oxidative stress. This antibody, raised in rabbits, is highly specific and sensitive for detecting Peroxiredoxin 4 in various samples.Peroxiredoxin 4 is involved in maintaining redox balance within cells and is implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. By using the KO Validated Peroxiredoxin 4 Polyclonal Antibody, researchers can effectively study the expression and function of this enzyme in different experimental settings.
This antibody has been rigorously validated for use in Western blotting, immunofluorescence, and immunohistochemistry applications, providing reliable and reproducible results. Its ability to specifically target Peroxiredoxin 4 makes it a valuable tool for investigating the role of this enzyme in disease pathogenesis and developing potential therapeutic strategies.
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
Purification Method:
Affinity purification
Gene ID:
10549
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Peroxiredoxin 4 (Peroxiredoxin 4 (PRDX4)) antibody (CAB1486) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
