Peroxiredoxin 3 (PRDX3) Rabbit Polyclonal Antibody (CAB13074)
- SKU:
- CAB13074
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Peroxiredoxin 3 (PRDX3) Rabbit Polyclonal Antibody |
SKU: | CAB13074 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 63-256 of human Peroxiredoxin 3 (Peroxiredoxin 3 (PRDX3)) (NP_006784.1). |
Sequence: | PAVT QHAP YFKG TAVV NGEF KDLS LDDF KGKY LVLF FYPL DFTF VCPT EIVA FSDK ANEF HDVN CEVV AVSV DSHF SHLA WINT PRKN GGLG HMNI ALLS DLTK QISR DYGV LLEG SGLA LRGL FIID PNGV IKHL SVND LPVG RSVE ETLR LVKA FQYV ETHG EVCP ANWT PDSP TIKP SPAA SKEY FQKV NQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | AOP1; MER5; AOP-1; PPPCD; SP-22; HBC189; SCAR32; PRO1748; prx-III; Peroxiredoxin 3 (PRDX3) |
Positive Sample: | U-87MG,HeLa,LO2,A-549,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.
Purification Method: | Affinity purification |
Gene ID: | 10935 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |