null

PRDX3 Monoclonal Antibody [PAT1F8AT] (CPAB0230)

SKU:
CPAB0230
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG3
Clone:
PAT1F8AT
Applications:
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

PRDX3 Monoclonal Antibody [PAT1F8AT] (CPAB0230)

The PRDX3 Polyclonal Antibody (CPAB0230) is a valuable tool for researchers studying peroxiredoxin 3 (PRDX3), a key antioxidant enzyme that plays a crucial role in protecting cells from oxidative damage. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.PRDX3 is a mitochondrial protein involved in reducing hydrogen peroxide and protecting cells from oxidative stress. Research has shown that dysregulation of PRDX3 is associated with various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

By targeting PRDX3, researchers can gain valuable insights into the mechanisms of oxidative stress and potentially develop new therapies for these conditions.With its ability to specifically bind to PRDX3, the CPAB0230 antibody enables accurate detection and analysis of PRDX3 in different cell types, making it an essential tool for studies in biology, medicine, and pharmacology. By understanding the functions and regulation of PRDX3, researchers can advance our knowledge of cellular oxidative stress and potentially identify new therapeutic targets for a range of diseases.

Product Name:PRDX3 Antibody
Product Sku:CPAB0230
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PRDX3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PRDX3 protein 63-256 amino acids purified from Ecoli.
Clone:PAT1F8AT.
Reactivity:Human
Applications:ELISA, Flow Cytometry
Purification Method:PRDX3 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG3
Background:PRDX3 is part of the peroxiredoxin family of antioxidant enzymes, that reduces hydrogen peroxide and alkyl hydroperoxides. PRDX3 is particularly located in the mitochondria and involved in the regulation of cellular redox status by serving as a primary line of defense against H2O2 produced during respiration. PRDX3 is a significant regulator of the abundance of mitochondrial H(2)O(2), which itself promotes apoptosis in cooperation with other mediators of apoptotic signaling. PRDX3 mitochondrial protein is significantly decreased in Alzheimer Disease and Down Syndrome.
Synonyms:AOP1, MER5, AOP-1, SP-22, PRO1748, MGC24293, MGC104387, PRDX3, Thioredoxin-dependent peroxide reductase mitochondrial, Peroxiredoxin-3, PRX III, Antioxidant protein 1, Protein MER5 homolog, HBC189.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products