The PRDX1 Polyclonal Antibody (CAB16412) is a valuable tool for researchers studying Peroxiredoxin-1 (PRDX1), a crucial antioxidant enzyme involved in regulating cellular redox balance. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it suitable for use in various experimental techniques such as Western blotting.PRDX1 is known to play a critical role in protecting cells from oxidative stress and maintaining cellular homeostasis. Dysregulation of PRDX1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
By using the PRDX1 Polyclonal Antibody, researchers can explore the expression levels and localization of PRDX1 in different cell types, shedding light on its function and potential therapeutic implications.This antibody is an essential tool for investigating the involvement of PRDX1 in different physiological and pathological processes, providing valuable insights into the development of novel treatment strategies. Its high affinity and specificity make it a reliable choice for immunology, cancer research, and other fields where the study of PRDX1 is of interest.
Product Name:
Peroxiredoxin 1/PAG Rabbit Polyclonal Antibody
SKU:
CAB16412
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human Peroxiredoxin 1/PAG (NP_001189360.1).
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
5052
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat liver, using Peroxiredoxin 1/PAG Rabbit pAb (CAB16412) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
