The PRDX1 Polyclonal Antibody (CAB13524) is a powerful tool for researchers studying PRDX1, a crucial antioxidant enzyme involved in regulating cellular redox balance. This antibody, generated in rabbits, exhibits high specificity towards human samples and has been validated for use in Western blot assays. By binding to the PRDX1 protein, it enables precise detection and analysis in various cell types, making it well-suited for investigations in oxidative stress, cancer biology, and neurodegenerative diseases.PRDX1, also known as peroxiredoxin-1, plays a pivotal role in defending cells against oxidative damage and maintaining cellular health by scavenging harmful reactive oxygen species. Dysregulation of PRDX1 has been linked to various pathologies, including cancer progression, neurodegenerative disorders, and cardiovascular diseases.
By unraveling the molecular mechanisms underlying PRDX1 function, researchers can uncover potential therapeutic targets for mitigating oxidative stress-related conditions and advancing personalized medicine strategies.In summary, the PRDX1 Polyclonal Antibody (CAB13524) offers a reliable tool for researchers seeking to explore the multifaceted roles of PRDX1 in health and disease. Its specificity, sensitivity, and versatility make it a valuable asset for studies aimed at unraveling the intricate interplay between oxidative stress, cellular signaling pathways, and disease pathogenesis.
Product Name:
Peroxiredoxin 1/PAG Rabbit Polyclonal Antibody
SKU:
CAB13524
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human Peroxiredoxin 1/PAG (NP_001189360.1).
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
5052
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Peroxiredoxin 1/PAG antibody (CAB13524) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
