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PRDX1 Monoclonal Antibody [PAT1D8AT] (CPAB0151)

SKU:
CPAB0151
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT1D8AT
Applications:
WB
ELISA
€149

Description

system_update_alt Datasheet

PRDX1 Monoclonal Antibody [PAT1D8AT] (CPAB0151)

The PRDX1 Polyclonal Antibody (CPAB0151) is a valuable tool for researchers studying peroxiredoxin 1 (PRDX1), a key antioxidant enzyme involved in regulating cellular redox balance and protecting cells from oxidative damage. This antibody, produced in rabbits, exhibits high reactivity with human samples and is optimized for use in Western blot applications.PRDX1, also known as thioredoxin peroxidase, is essential for maintaining cellular homeostasis by scavenging reactive oxygen species and preventing oxidative stress-induced cell damage. Dysregulation of PRDX1 is associated with various diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions.

By targeting PRDX1, researchers can gain insights into the mechanisms underlying these diseases and identify potential therapeutic strategies.This polyclonal antibody specifically recognizes the PRDX1 protein, enabling precise detection and analysis in different cell types and tissue samples. Its reliable performance in Western blot assays makes it an ideal choice for studies investigating the role of PRDX1 in oxidative stress, inflammation, and disease pathology. Enhance your research with the PRDX1 Polyclonal Antibody and unlock new insights into cellular redox regulation and disease mechanisms.

Product Name:PRDX1 Antibody
Product Sku:CPAB0151
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PRDX1 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PRDX1 amino acids 1-199 purified from Ecoli.
Clone:PAT1D8AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:PRDX1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:PRDX1 is part of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. PRDX1 is an important protector of red blood cells against reactive oxygen species and in tumor prevention. PRDX1 is antioxidant protective in cells, and contributes to the antiviral activity of CD8(+) T-cells. PRDX1 has a proliferative effect and is involved in cancer development or progression. Peroxiredoxin-1 is plays a role in redox regulation of the cell. Peroxiredoxin decreases peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. Peroxiredoxin is involved in eliminating peroxides generated during metabolism. Peroxiredoxin participates in the signaling cascades of growth factors and TNF-alpha by regulating the intracellular concentrations of h(2)o(2).
Synonyms:Peroxiredoxin-1, EC 1.11.1.15, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2, Proliferation-associated gene protein, Natural killer cell-enhancing factor A, NKEF-A, PRDX1, TDPX2, PRDX-1, PAG, PAGA, PRX1, PAGB, PRXI, MSP23, NKEFA.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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