The PRDM4 Polyclonal Antibody (PAC011450) offered by Assay Genie is a valuable tool for researchers studying PRDM4, a transcription factor involved in gene expression regulation. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the PRDM4 protein, this antibody enables the detection and analysis of PRDM4 in various cell types, providing insights into its role in cellular processes and diseases.PRDM4, also known as PR domain zinc finger protein 4, has been implicated in a variety of biological functions, including cell differentiation, proliferation, and apoptosis.
Dysregulation of PRDM4 expression has been linked to cancer development and progression, making it a promising target for cancer research and therapy development. By understanding the mechanisms by which PRDM4 influences gene expression, researchers can uncover new therapeutic approaches for cancer treatment and other diseases.Overall, the PRDM4 Polyclonal Antibody (PAC011450) is a reliable tool for investigating the functions and molecular mechanisms of PRDM4 in biological processes and diseases, offering valuable insights that can lead to advancements in the field of biomedical research.
PRDM4: May function as a transcription factor involved in cell differentiation.Protein type: Methyltransferase, protein lysine, predicted; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 12q23-q24.1Cellular Component: nucleusMolecular Function: methyltransferase activity; DNA binding; zinc ion bindingBiological Process: transcription from RNA polymerase II promoter; methylation; cell proliferation; nerve growth factor receptor signaling pathway; regulation of transcription, DNA-dependent; signal transduction; negative regulation of cell cycle
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]
