PRDM2 Rabbit Polyclonal Antibody (CAB13157)
- SKU:
- CAB13157
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PRDM2 Rabbit Polyclonal Antibody |
SKU: | CAB13157 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-176 of human PRDM2 (NP_036363.2). |
Sequence: | MNQN TTEP VAAT ETLA EVPE HVLR GLPE EVRL FPSA VDKT RIGV WATK PILK GKKF GPFV GDKK KRSQ VKNN VYMW EVYY PNLG WMCI DATD PEKG NWLR YVNW ACSG EEQN LFPL EINR AIYY KTLK PIAP GEEL LVWY NGED NPEI AAAI EEER ASAR SKRS SPKS RKGK KKSQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RIZ; KMT8; RIZ1; RIZ2; KMT8A; MTB-ZF; HUMHOXY1; PRDM2 |
Positive Sample: | U-87MG,LO2,MCF7,Mouse brain,Mouse liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 189kDa |
Observed MW: | 300kDa |
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7799 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |