The PRDM2 Polyclonal Antibody (CAB13157) is a valuable tool for researchers studying the PRDM2 protein, a transcriptional regulator involved in oncogenesis and tumor suppression. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the PRDM2 protein, this antibody allows for the detection and analysis of PRDM2 expression in various cell types, making it an ideal choice for studies in cancer research and molecular biology.PRDM2, also known as RIZ1, is a critical player in the regulation of gene expression and cell growth, making it a key target for investigation in cancer biology.
Dysregulation of PRDM2 has been linked to various cancers, highlighting its importance as a potential therapeutic target. By understanding the function and activity of PRDM2, researchers can gain insights into the mechanisms underlying tumorigenesis and potentially develop novel treatment strategies for cancer patients.Overall, the PRDM2 Polyclonal Antibody (CAB13157) offers researchers a reliable tool for studying the role of PRDM2 in cancer development and progression. Its high specificity and sensitivity make it a valuable asset for research projects aiming to unravel the complex molecular pathways involved in oncogenesis.
Product Name:
PRDM2 Rabbit Polyclonal Antibody
SKU:
CAB13157
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-176 of human PRDM2 (NP_036363.2).
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7799
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PRDM2 antibody (CAB13157) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
