PRDM12 Rabbit Polyclonal Antibody (CAB17746)
- SKU:
- CAB17746
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PRDM12 Rabbit Polyclonal Antibody |
SKU: | CAB17746 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-330 of human PRDM12 (NP_067632.2). |
Sequence: | LGIF SKTW IKAG TEMG PFTG RVIA PEHV DICK NNNL MWEV FNED GTVR YFID ASQE DHRS WMTY IKCA RNEQ EQNL EVVQ IGTS IFYK AIEM IPPD QELL VWYG NSHN TFLG IPGV PGLE EDQK KNKH EDFH PADS AAGP AGRM RCVI CHRG FNSR SNLR SHMR IHTL DKPF VCRF CNRR FSQS STLR NHVR LHTG ERPY KCQV CQSA YSQL AGLR AHQK SARH RPPS TAL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PFM9; HSAN8; PRDM12 |
Positive Sample: | U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | nucleoplasm, nucleus |
Calculated MW: | 40kDa |
Observed MW: | 45kDa |
This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia.
Purification Method: | Affinity purification |
Gene ID: | 59335 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |