The PRDM11 Polyclonal Antibody (CAB8502) is a valuable tool for researchers studying the PRDM11 protein, a key regulator of gene expression and cell differentiation. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to PRDM11, this antibody allows for precise detection and analysis of the protein in various cell types, making it an essential component for studies in developmental biology, epigenetics, and cancer research.
PRDM11, a member of the PRDM family of transcription factors, plays a crucial role in the regulation of gene expression during development and differentiation. Its involvement in these processes makes it a potential target for therapeutic interventions in diseases such as cancer and developmental disorders. By understanding the function of PRDM11, researchers can uncover new insights into cellular processes and potentially develop novel treatment strategies for a variety of conditions.
Product Name:
PRDM11 Rabbit Polyclonal Antibody
SKU:
CAB8502
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 228-477 of human PRDM11 (NP_001243625.1).
Predicted to enable chromatin binding activity. Involved in several processes, including negative regulation of cell growth; positive regulation of fibroblast apoptotic process; and regulation of transcription, DNA-templated. Located in cytosol and nucleus.
Purification Method:
Affinity purification
Gene ID:
56981
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PRDM11 antibody (CAB8502) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
