The PRDM1 Polyclonal Antibody (CAB1960) is a valuable tool for researchers studying PRDM1, a transcription factor with key roles in immune regulation and cell differentiation. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting PRDM1 in human samples, making it ideal for Western blot applications.PRDM1, also known as Blimp-1, is involved in the differentiation of B cells into plasma cells and plays a crucial role in immune response modulation. Dysregulation of PRDM1 has been associated with various diseases, including cancer and autoimmune disorders.
By targeting PRDM1 with this antibody, researchers can gain insights into its functions and potential therapeutic implications in these disease contexts.Overall, the PRDM1 Polyclonal Antibody (CAB1960) is a reliable tool for investigating PRDM1 activity and its impact on immune regulation, making it a valuable asset for studies in immunology, cancer research, and autoimmune diseases.
Product Name:
PRDM1 Rabbit Polyclonal Antibody
SKU:
CAB1960
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-210 of human PRDM1 (NP_001189.2).
This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Purification Method:
Affinity purification
Gene ID:
639
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using (CAB1960) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
