PRC1 Rabbit Polyclonal Antibody (CAB7029)
- SKU:
- CAB7029
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | PRC1 Rabbit Polyclonal Antibody |
SKU: | CAB7029 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 351-620 of human PRC1 (NP_003972.1). |
Sequence: | LFEG VQKW EETW RLFL EFER KASD PNRF TNRG GNLL KEEK QRAK LQKM LPKL EEEL KARI ELWE QEHS KAFM VNGQ KFME YVAE QWEM HRLE KERA KQER QLKN KKQT ETEM LYGS APRT PSKR RGLA PNTP GKAR KLNT TTMS NATA NSSI RPIF GGTV YHSP VSRL PPSG SKPV AAST CSGK KTPR TGRH GANK ENLE LNGS ILSG GYPG SAPL QRNF SINS VAST YSEF AKDP SLSD SSTV GLQR ELSK ASKS DATS GILN STNI QS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ASE1; PRC1 |
Positive Sample: | MCF7,Jurkat,293T,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Midbody, Nucleus, cytoskeleton, spindle pole. |
Calculated MW: | 72kDa |
Observed MW: | 72kDa |
This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 9055 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |