The PRB1 Polyclonal Antibody (PACO59864) is a valuable tool for researchers studying PRB1, a protein involved in multiple cellular processes, particularly in the context of cancer biology. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications.PRB1, also known as protease inhibitor 1, plays a crucial role in regulating protease activity and maintaining cellular homeostasis. Dysregulation of PRB1 has been implicated in various diseases, particularly in cancer progression and metastasis.
By targeting PRB1, researchers can gain insights into the mechanisms underlying these pathologies and potentially identify new therapeutic approaches.The PRB1 Polyclonal Antibody enables precise detection and analysis of PRB1 expression in diverse cell types, offering researchers a powerful tool for investigating the functional roles of PRB1 in disease development and progression. Its reliability and specificity make it an indispensable resource for studies in cancer research and beyond.
Antibody Name:
PRB1 Antibody (PACO59864)
Antibody SKU:
PACO59864
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Basic salivary proline-rich protein 1 protein (17-92AA)
Western Blot. Positive WB detected in: K562 whole cell lysate. All lanes: PRB1 antibody at 3.16µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 39 kDa. Observed band size: 39 kDa.
This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature peptides before secretion from the parotid glands. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Medium" allele. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Nov 2015]