The PRAMEF17 Polyclonal Antibody (PACO63371) is a crucial tool for researchers studying the PRAMEF17 protein, a tumor-associated antigen that is overexpressed in various cancer types. This antibody, generated from rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot analyses. By targeting the PRAMEF17 protein, this antibody enables accurate detection and analysis in diverse cellular contexts, offering significant insights for investigations in cancer biology and therapeutic development.PRAMEF17, a member of the PRAME family of cancer-testis antigens, plays a pivotal role in tumorigenesis and cancer progression by modulating cell growth, survival, and migration.
Its aberrant expression in cancer cells highlights its potential as a biomarker for cancer diagnosis and prognosis. Furthermore, its role in immune evasion mechanisms underscores the importance of studying PRAMEF17 for the development of novel immunotherapies targeting cancer-specific antigens.The PRAMEF17 Polyclonal Antibody (PACO63371) serves as an invaluable tool for researchers aiming to unravel the molecular mechanisms underlying cancer development and progression. Its high specificity and sensitivity, coupled with its ability to target the PRAMEF17 protein, make it an essential component in advancing our understanding of cancer biology and paving the way for innovative therapeutic strategies.
Antibody Name:
PRAMEF17 Antibody (PACO63371)
Antibody SKU:
PACO63371
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human PRAME family member 17 protein (69-259AA)
Western Blot. Positive WB detected in: U87 whole cell lysate. All lanes: PRAMEF17 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 55 kDa. Observed band size: 55 kDa.
Synonyms:
PRAME family member 17, PRAMEF17
UniProt Protein Function:
PRAMEF17: Belongs to the PRAME familyChromosomal Location of Human Ortholog: 1p36.21Biological Process: negative regulation of apoptosis; negative regulation of cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation
