PRAME Rabbit Polyclonal Antibody (CAB14507)
- SKU:
- CAB14507
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | PRAME Rabbit Polyclonal Antibody |
SKU: | CAB14507 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRAME (NP_006106.1). |
Sequence: | MERR RLWG SIQS RYIS MSVW TSPR RLVE LAGQ SLLK DEAL AIAA LELL PREL FPPL FMAA FDGR HSQT LKAM VQAW PFTC LPLG VLMK GQHL HLET FKAV LDGL DVLL AQEV RPRR WKLQ VLDL RKNS HQDF WTVW SGNR ASLY SFPE PEAA QPMT KKRK VDGL STEA EQPF IPVE VLVD LFLK EGAC DELF SYLI EKVK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MAPE; OIP4; CT130; OIP-4; PRAME |
Positive Sample: | U2OS,U-251MG,Mouse liver,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Nucleus. |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23532 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |