The PQBP1 Polyclonal Antibody (CAB18680) is a valuable tool for researchers studying PQBP1, a protein involved in various cellular processes such as transcription regulation and RNA processing. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.PQBP1, also known as polyglutamine-binding protein 1, is implicated in neural development and has been associated with intellectual disabilities and other neurodevelopmental disorders.
Its role in gene expression regulation makes it a promising target for studies in neuroscience and genetics.By using the PQBP1 Polyclonal Antibody, researchers can easily detect and analyze PQBP1 protein levels in a variety of cell types, aiding in the understanding of its function and potential implications in disease. This antibody is a valuable tool for those investigating the molecular mechanisms underlying neurodevelopmental disorders and seeking potential therapeutic targets.
Product Name:
Pqbp1 Rabbit Polyclonal Antibody
SKU:
CAB18680
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-263 of mouse Pqbp1 (NP_062351.2).
Predicted to enable double-stranded DNA binding activity; protein C-terminus binding activity; and ribonucleoprotein complex binding activity. Involved in alternative mRNA splicing, via spliceosome and neuron projection development. Acts upstream of or within regulation of dendrite morphogenesis. Located in cytoplasmic stress granule; neuronal ribonucleoprotein granule; and nuclear speck. Is expressed in several structures, including 1st branchial arch maxillary component; adrenal cortex; central nervous system; eye; and limb. Used to study Renpenning syndrome. Human ortholog(s) of this gene implicated in Renpenning syndrome. Orthologous to human PQBP1 (polyglutamine binding protein 1).
Purification Method:
Affinity purification
Gene ID:
54633
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using Pqbp1 Rabbit pAb (CAB18680) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
