The PPT2 Polyclonal Antibody (CAB12251) is specifically designed for research involving the PPT2 protein, a key enzyme involved in lipid metabolism and autophagy. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the PPT2 protein, this antibody allows for the detection and analysis of PPT2 in various cell types, making it an ideal tool for studies in lipid metabolism, autophagy, and related research areas.The PPT2 enzyme plays a crucial role in the breakdown of lipid molecules and the regulation of autophagy, a process essential for cellular homeostasis and the removal of damaged organelles. Dysregulation of PPT2 activity has been linked to various diseases, including metabolic disorders, neurodegenerative diseases, and cancer.
Investigating the function of PPT2 using this antibody can provide valuable insights into the mechanisms underlying these conditions and may lead to the development of novel therapeutic strategies targeting lipid metabolism and autophagy pathways.Overall, the PPT2 Polyclonal Antibody (CAB12251) offers researchers a reliable tool for studying the role of PPT2 in health and disease, with potential applications in drug discovery, biomarker identification, and mechanistic studies. Its high specificity and sensitivity make it a valuable asset for researchers interested in exploring the complex interplay between lipid metabolism, autophagy, and cellular physiology.
Product Name:
PPT2 Rabbit Polyclonal Antibody
SKU:
CAB12251
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-302 of human PPT2 (NP_005146.4).
This gene encodes a member of the palmitoyl-protein thioesterase family. The encoded glycosylated lysosomal protein has palmitoyl-CoA hydrolase activity in vitro, but does not hydrolyze palmitate from cysteine residues in proteins. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream EGFL8 (EGF-like-domain, multiple 8) gene.
Purification Method:
Affinity purification
Gene ID:
9374
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse liver, using PPT2 Rabbit pAb (CAB12251) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
