PPT1 Rabbit Polyclonal Antibody (CAB14769)
- SKU:
- CAB14769
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | PPT1 Rabbit Polyclonal Antibody |
SKU: | CAB14769 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-306 of human PPT1 (NP_000301.1). |
Sequence: | DPPA PLPL VIWH GMGD SCCN PLSM GAIK KMVE KKIP GIYV LSLE IGKT LMED VENS FFLN VNSQ VTTV CQAL AKDP KLQQ GYNA MGFS QGGQ FLRA VAQR CPSP PMIN LISV GGQH QGVF GLPR CPGE SSHI CDFI RKTL NAGA YSKV VQER LVQA EYWH DPIK EDVY RNHS IFLA DINQ ERGI NESY KKNL MALK KFVM VKFL NDSI VDPV DSEW FGFY RSGQ AKET IPLQ ETSL YTQD RLGL KEMD NAGQ LVFL ATEG DHLQ LSEE WFYA HIIP FLG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PPT; CLN1; INCL; PPT1 |
Positive Sample: | LO2,Mouse brain,Mouse kidney,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome. |
Calculated MW: | 34kDa |
Observed MW: | 33kDa |
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5538 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |