The PPP6R3 Polyclonal Antibody (CAB17177) is a valuable tool for researchers studying PPP6R3, a protein involved in regulating cell division and cell cycle progression. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to PPP6R3, this antibody allows for the detection and analysis of this important protein in various cell types.PPP6R3 is a key player in cellular processes such as DNA replication and repair, making it a target of interest in cancer research and other studies related to cell proliferation.
By understanding the role of PPP6R3, researchers can gain insights into how disruptions in its function may contribute to diseases like cancer and developmental disorders. This antibody is a valuable tool for investigating the function and regulation of PPP6R3 in a variety of biological contexts.
Product Name:
PPP6R3 Rabbit Polyclonal Antibody
SKU:
CAB17177
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PPP6R3 (NP_060782.2).
Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).
Purification Method:
Affinity purification
Gene ID:
55291
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PPP6R3 Rabbit pAb (CAB17177) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
