Calcineurin A Rabbit Polyclonal Antibody (CAB1063)
- SKU:
- CAB1063
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Calcineurin A Rabbit Polyclonal Antibody |
SKU: | CAB1063 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-511 of human Calcineurin A (NP_001124163.1). |
Sequence: | MSEP KAID PKLS TTDR VVKA VPFP PSHR LTAK EVFD NDGK PRVD ILKA HLMK EGRL EESV ALRI ITEG ASIL RQEK NLLD IDAP VTVC GDIH GQFF DLMK LFEV GGSP ANTR YLFL GDYV DRGY FSIE CVLY LWAL KILY PKTL FLLR GNHE CRHL TEYF TFKQ ECKI KYSE RVYD ACMD AFDC LPLA ALMN QQFL CVHG GLSP EINT LDDI RKLD RFKE PPAY GPMC DILW SDPL EDFG NEKT QEHF THNT VRGC SYFY SYPA VCEF LQHN NLLS ILRA HEAQ DAGY RMYR KSQT TGFP SLIT IFSA PNYL DVYN NKAA VLKY ENNV MNIR QFNC SPHP YWLP NFMD VFTW SLPF VGEK VTEM LVNV LNIC SDDE LGSE EDGF DGAT AAAR KEVI RNKI RAIG KMAR VFSV LREE SESV LTLK GLTP TGML PSGV LSGG KQTL QSAI KGFS PQHK ITSF EEAK GLDR INER MPPR RDAM PSDA NLNS INKA LTSE TNGT DSNG SNSS NIQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CALN; CCN1; CNA1; CALNA; DEE91; IECEE; PPP2B; ACCIID; CALNA1; IECEE1; Calcineurin A |
Positive Sample: | HeLa,SH-SY5Y,THP-1,A-549,Mouse brain,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Nucleus, sarcolemma. |
Calculated MW: | 59kDa |
Observed MW: | 57kDa |
Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia.
Purification Method: | Affinity purification |
Gene ID: | 5530 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |