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PPP3CA Monoclonal Antibody [PAT1E11AT] (CPAB0694)

SKU:
CPAB0694
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b 
Clone:
PAT1E11AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

PPP3CA Monoclonal Antibody [PAT1E11AT] (CPAB0694)

The PPP3CA Polyclonal Antibody (CPAB0694) is a valuable tool for research involving the PPP3CA protein, also known as Protein Phosphatase 3 catalytic subunit alpha. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.PPP3CA is a key regulator of cellular processes, particularly in signal transduction pathways and gene expression. Its involvement in cell growth, proliferation, and apoptosis makes it a crucial target for studies in cancer research and other diseases related to abnormal cell function.

By utilizing the PPP3CA Polyclonal Antibody, researchers can accurately detect and analyze PPP3CA protein levels in different cell types, allowing for precise investigation into its role in various physiological and pathological processes.Overall, the PPP3CA Polyclonal Antibody is a reliable tool for researchers interested in understanding the function of PPP3CA and its potential implications in disease development and progression. Its high specificity and sensitivity make it an essential component of studies aiming to elucidate the molecular mechanisms underlying important cellular functions.

Product Name:PPP3CA antibody
Product Sku:CPAB0694
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PPP3CA mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPP3CA protein 1-511 amino acids purified from Ecoli.
Clone:PAT1E11AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:PPP3CA antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b 
Background:PPP3CA (aka Calcineurin A) is a major soluble calmodulin binding protein in the brain and a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively limited substrate specificity. PPP3CA activates the T cells of the immune system and can be blocked by drugs. PPP3CA activates NFATc (a transcription factor) by dephosphorylating it. The activated NFATc is subsequently translocated into the nucleus, where it upregulates the expression of interleukin 2.
Synonyms:Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform, PPP3CA, CALNA, CAN, CALN, CCN1, CNA1, PPP2B, CALNA1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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