The PPP2R5D Polyclonal Antibody (CAB15707) is a valuable tool for researchers studying PPP2R5D, a regulatory subunit of the protein phosphatase 2A (PP2A) enzyme. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting. By binding to PPP2R5D, this antibody allows for the detection and analysis of this important protein in different cell types, making it an essential tool for studies in molecular biology and cell signaling pathways.PP2A is a critical enzyme involved in the regulation of numerous cellular processes, including cell growth, division, and differentiation.
PPP2R5D is one of the regulatory subunits that determine the substrate specificity and activity of PP2A, making it a key player in cellular signaling cascades. Research on PPP2R5D is essential for understanding its role in various physiological and pathological conditions, such as cancer, neurodegenerative diseases, and metabolic disorders. By using the PPP2R5D Polyclonal Antibody, researchers can further explore the functions and mechanisms of PPP2R5D, paving the way for potential therapeutic interventions targeting this important protein.
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
5528
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PP2A-B56δ/PR61δ/PPP2R5D Rabbit pAb (CAB15707) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
