PP2A-B56γ/PR61γ/PPP2R5C Rabbit Polyclonal Antibody (CAB5480)
- SKU:
- CAB5480
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
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Description
Product Name: | PP2A-B56γ/PR61γ/PPP2R5C Rabbit Polyclonal Antibody |
SKU: | CAB5480 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human PP2A-B56γ/PR61γ/PP2A-B56γ/PR61γ/PPP2R5C (NP_848702.1). |
Sequence: | MLTC NKAG SRMV VDAA NSNG PFQP VVLL HIRD VPPA DQEK LFIQ KLRQ CCVL FDFV SDPL SDLK WKEV KRAA LSEM VEYI THNR NVIT EPIY PEVV HMFA VNMF RTLP PSSN PTGA EFDP EEDE PTLE AAWP HLQL VYEF FLRF LESP DFQP NIAK KYID QKFV LQLL ELFD SEDP RERD FLKT TLHR IYGK FLGL RAYI RKQI NNIF YRFI YETE HHNG IAEL LEIL GSII NGFA LPLK EEHK IFLL KVLL PLHK VKSL SVYH PQLA YCVV QFLE KDST LTEP VVMA LLKY WPKT HSPK EVMF LNEL EEIL DVIE PSEF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | B56G; PR61G; B56gamma; PP2A-B56γ/PR61γ/PPP2R5C |
Positive Sample: | MCF7,K-562,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, centromere. |
Calculated MW: | 61kDa |
Observed MW: | 68-71kDa |
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 5527 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |