The PPP2R5C Polyclonal Antibody (CAB5480) is a vital tool for researchers studying PPP2R5C, a regulatory subunit of protein phosphatase 2A that plays a crucial role in cell growth and division. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blotting applications. By binding specifically to the PPP2R5C protein, this antibody enables the detection and analysis of PPP2R5C levels in various cell types, providing valuable insights for studies in cell biology and cancer research.PPP2R5C is a key player in the control of cell cycle progression and cell proliferation, making it a potential target for therapeutic interventions in cancer and other proliferative disorders.
Understanding the regulatory mechanisms involving PPP2R5C is crucial for deciphering its role in cellular processes and identifying potential drug targets for cancer treatment. The PPP2R5C Polyclonal Antibody is a valuable tool for researchers aiming to dissect the functions and regulatory pathways associated with PPP2R5C, ultimately advancing our understanding of its role in health and disease.
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
5527
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PP2A-B56γ/PR61γ/PP2A-B56γ/PR61γ/PPP2R5C antibody (CAB5480) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
