The PPP2R3B Polyclonal Antibody (CAB8489) is a valuable tool for researchers studying PPP2R3B, a regulatory subunit of protein phosphatase 2A. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for use in Western blot applications. By binding to PPP2R3B, this antibody enables precise detection and analysis of the protein in various cell types.PPP2R3B is known to play a crucial role in regulating cellular processes such as cell growth, division, and signaling pathways. Its dysregulation has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions.
Research on PPP2R3B is essential for developing a deeper understanding of its function and utilizing it as a potential therapeutic target in cancer and other diseases.By using the PPP2R3B Polyclonal Antibody, researchers can delve deeper into the mechanisms of PPP2R3B in cellular processes and disease pathogenesis, ultimately advancing our knowledge and potentially leading to novel treatment strategies.
Product Name:
PPP2R3B Rabbit Polyclonal Antibody
SKU:
CAB8489
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 356-575 of human PPP2R3B (NP_037371.2).
Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''.
Purification Method:
Affinity purification
Gene ID:
28227
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PPP2R3B antibody (CAB8489) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
