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PPP2R2C Antibody (PACO11434)

SKU:
PACO11434
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€669

Description

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PPP2R2C Antibody (PACO11434)

The PPP2R2C Polyclonal Antibody (PAC011434) is a valuable tool for research involving PPP2R2C, a regulatory subunit of the protein phosphatase 2A (PP2A) complex that plays a critical role in cell signaling and cell cycle regulation. This antibody, produced in rabbits, is highly specific to human PPP2R2C and has been validated for use in various applications, including Western blot and immunofluorescence.PPP2R2C is involved in the dephosphorylation of key signaling molecules, making it an important player in the regulation of cellular processes such as cell proliferation, apoptosis, and differentiation. Dysregulation of PPP2R2C has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

Therefore, studying PPP2R2C expression and activity is crucial for understanding its role in health and disease.With its high specificity and sensitivity, the PPP2R2C Polyclonal Antibody is an essential tool for researchers in the fields of molecular biology, biochemistry, and cancer research. By enabling the detection and analysis of PPP2R2C in different cell types and tissues, this antibody contributes to advancing our knowledge of the complex mechanisms underlying cellular signaling and disease progression.

Antibody Name:PPP2R2C Antibody (PACO11434)
Antibody SKU:PACO11434
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human PPP2R2C
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:protein phosphatase 2 (formerly 2A), regulatory subunit B, γ isoform;PPP2R2C;B55-GAMMA;IMYPNO;IMYPNO1;MGC33570;PR52;PR55G ;
UniProt Protein Function:PPP2R2C: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Belongs to the phosphatase 2A regulatory subunit B family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 4p16.1

Molecular Function:protein binding

NCBI Summary:The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Code:Q9Y2T4
NCBI GenInfo Identifier:145559437
NCBI Gene ID:5522
NCBI Accession:Q9Y2T4.4
UniProt Secondary Accession:Q9Y2T4,Q7Z4V7, Q8NEC4, Q9H3G7, A8MSY7, B7Z3Y1,
UniProt Related Accession:Q9Y2T4
Molecular Weight:50,636 Da
NCBI Full Name:Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform
NCBI Synonym Full Names:protein phosphatase 2 regulatory subunit Bgamma
NCBI Official Symbol:PPP2R2C  
NCBI Official Synonym Symbols:PR52; PR55G; IMYPNO; IMYPNO1; B55-GAMMA  
NCBI Protein Information:protein phosphatase 2, regulatory subunit B, gamma
UniProt Protein Name:Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform
UniProt Synonym Protein Names:IMYPNO1; PP2A subunit B isoform B55-gamma; PP2A subunit B isoform PR55-gamma; PP2A subunit B isoform R2-gamma; PP2A subunit B isoform gamma
Protein Family:Serine/threonine-protein phosphatase
UniProt Gene Name:PPP2R2C  
UniProt Entry Name:2ABG_HUMAN

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