null

PP2A-Aα/PR65α/PPP2R1A Rabbit Polyclonal Antibody (CAB5799)

SKU:
CAB5799
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-PPP2R1A Antibody CAB5799
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-PPP2R1A Antibody CAB5799
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PP2A-Aα/PR65α/PPP2R1A Rabbit Polyclonal Antibody
SKU:CAB5799
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PP2A-Aalpha/PR65α/PP2A-Aα/PR65α/PPP2R1A (NP_055040.2).
Sequence:MAAA DGDD SLYP IAVL IDEL RNED VQLR LNSI KKLS TIAL ALGV ERTR SELL PFLT DTIY DEDE VLLA LAEQ LGTF TTLV GGPE YVHC LLPP LESL ATVE ETVV RDKA VESL RAIS HEHS PSDL EAHF VPLV KRLA GGDW FTSR TSAC GLFS VCYP RVSS AVKA ELRQ YFRN LCSD DTPM VRRA AASK LGEF AKVL ELDN VKSE IIPM FSNL ASDE QDSV RLLA VEAC VNIA QLLP QEDL EALV MPTL RQAA EDKS WRVR YMVA DKFT EL
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:10 - 1:100
Synonyms:MRD36; PP2AA; PR65A; PP2AAALPHA; PP2A-Aalpha; PP2A-Aα/PR65α/PPP2R1A
Positive Sample:MCF7,HT-29,Mouse liver,Mouse brain,Mouse kidney,Rat liver,Rat brain
Conjugate:Unconjugated
Cellular Localization:Chromosome, Cytoplasm, centromere.
Calculated MW:65kDa
Observed MW:65kDa

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.

Purification Method:Affinity purification
Gene ID:5518
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using PP2A-Aalpha/PR65α/PP2A-Aα/PR65α/PPP2R1A Polyclonal Antibody (CAB5799) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

Related Products