The PPP2CB Polyclonal Antibody (CAB3122) is a valuable tool for researchers studying PPP2CB, a gene encoding a subunit of the protein phosphatase 2A enzyme complex. This enzyme plays a crucial role in regulating cell division, cell growth, and apoptosis. The antibody, produced in rabbits, displays high specificity and sensitivity for detecting PPP2CB in human samples, making it ideal for use in Western blot applications.PPP2CB is known to be involved in various cellular processes, including DNA damage response, cell cycle regulation, and signal transduction pathways. Dysregulation of PPP2CB has been linked to cancer development and progression, making it a potential target for cancer therapy research.
By enabling the detection and analysis of PPP2CB protein levels, this antibody is a valuable tool for investigating the role of PPP2CB in cancer biology and other cellular processes.Understanding the function and regulation of PPP2CB is essential for uncovering its potential as a therapeutic target in cancer treatment and other diseases. The PPP2CB Polyclonal Antibody (CAB3122) provides researchers with a reliable and versatile tool for studying the complex role of PPP2CB in cellular physiology and disease pathways.
Product Name:
PP2A Catalytic β Rabbit Polyclonal Antibody
SKU:
CAB3122
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human PP2A Catalytic β (NP_001009552.1).
Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, spindle pole.
Calculated MW:
36kDa
Observed MW:
36kDa
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit.
Purification Method:
Affinity purification
Gene ID:
5516
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PP2A Catalytic β Rabbit pAb (CAB3122) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
