The PPP1R9B Polyclonal Antibody (CAB17230) is a valuable research tool for studying PPP1R9B, a regulatory subunit of protein phosphatase 1 (PP1) that plays a crucial role in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PPP1R9B protein, this antibody allows for the detection and analysis of PPP1R9B expression in different cell types, making it an ideal choice for researchers in the fields of cell biology and signal transduction.
PPP1R9B is involved in the regulation of PP1 activity, which in turn influences processes such as cell division, cell growth, and cell signaling. Dysregulation of PP1 activity has been linked to various diseases, including cancer and neurological disorders, highlighting the importance of studying proteins like PPP1R9B. By gaining a better understanding of how PPP1R9B functions in cellular pathways, researchers can identify potential therapeutic targets for the treatment of these diseases.
Product Name:
PPP1R9B Rabbit Polyclonal Antibody
SKU:
CAB17230
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human PPP1R9B (NP_115984.3).
This gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has putative tumor suppressor function and decreased expression has been observed in tumors.
Purification Method:
Affinity purification
Gene ID:
84687
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PPP1R9B Rabbit pAb (CAB17230) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
