The PPP1R7 Polyclonal Antibody (CAB13041) is a valuable tool for researchers investigating PPP1R7, a regulatory subunit of protein phosphatase 1 (PP1) involved in cellular processes such as cell cycle progression and signal transduction. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for Western blot applications.PPP1R7, also known as spinophilin, plays a critical role in the regulation of PP1 activity, influencing various cellular functions including neuronal signaling and synaptic plasticity.
Dysregulation of PPP1R7 has been implicated in neurological disorders such as Alzheimer's disease and schizophrenia, highlighting its importance in brain function and pathology.By targeting PPP1R7 with this polyclonal antibody, researchers can gain insights into the role of PP1 in cellular signaling pathways and potentially identify novel therapeutic targets for neurological diseases. The versatility and reliability of this antibody make it an essential tool for studies in neuroscience and molecular biology.
Product Name:
PPP1R7 Rabbit Polyclonal Antibody
SKU:
CAB13041
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 281-360 of human PPP1R7 (NP_002703.1).
This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5510
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PPP1R7 Rabbit pAb (CAB13041) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
