The PPP1R16A Polyclonal Antibody (PAC022525) is a valuable tool for researchers studying PPP1R16A, a protein involved in diverse cellular processes such as cell cycle regulation, apoptosis, and DNA repair. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to PPP1R16A, this antibody allows for detection and analysis of the protein in various cell types, making it suitable for investigations in molecular biology and cancer research.
PPP1R16A, also known as inhibitor-3 (I-3), is a key player in controlling the activity of protein phosphatase 1 (PP1) and has been implicated in the regulation of cell growth and survival. Its involvement in fundamental cellular processes underscores its importance as a potential therapeutic target for conditions such as cancer and neurodegenerative diseases. Research on PPP1R16A is vital for uncovering its precise functions and developing strategies to manipulate its activity for therapeutic purposes.
Antibody Name:
PPP1R16A Antibody (PACO22525)
Antibody SKU:
PACO22525
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human PPP1R16A.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from Rat heart cells, using PPP1R16A antibody.
Background:
Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates By similarity.
Synonyms:
Myosin phosphatase-targeting subunit 3; MYPT3;
UniProt Protein Function:
PPP1R16A: Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.Protein type: Protein phosphatase, regulatory subunitChromosomal Location of Human Ortholog: 8q24.3Cellular Component: plasma membraneMolecular Function: protein binding
