Anti-PPP1R14C Antibody (PACO00997)

PPP1R14C Antibody (PACO00997)

SKU:

PACO00997

Product Type:

Antibody

Reactivity:

Human

Mouse

Rat

Host Species:

Rabbit

Isotype:

IgG

Applications:

ELISA

IHC

Antibody Type:

Polyclonal Antibody

Conjugation:

Unconjugated

Description

Description

DatasheetMSDS

PPP1R14C Antibody (PACO00997)

The PPP1R14C Polyclonal Antibody (PACO00997) is an essential tool for researchers studying the PPP1R14C protein, which plays a key role in cell cycle regulation and cell proliferation. Raised in rabbits, this antibody demonstrates high reactivity with human samples and has been validated for use in applications such as Western blotting.PPP1R14C, also known as protein phosphatase 1 regulatory subunit 14C, is involved in the dephosphorylation of target proteins, leading to the regulation of various cellular processes. Its function in cell cycle progression and proliferation makes it a crucial target for research in fields such as cancer biology, cell signaling, and developmental biology.

By detecting and analyzing PPP1R14C expression in different cell types, this antibody aids in understanding the protein's role in these processes.Furthermore, studying PPP1R14C can provide insights into potential therapeutic targets for diseases characterized by dysregulated cell growth, such as cancer. By unraveling the mechanisms by which PPP1R14C influences cell proliferation, researchers can develop targeted interventions to modulate these processes and potentially design novel treatment strategies.

PPP1R14C Antibody (PACO21902)

$503

Product Code:

PACO21902

Isotype:

IgG

Antibody Type:

Polyclonal Antibody

PPP1R14C Colorimetric Cell-Based ELISA (CBCAB01159)

$923

Product Code:

CBCAB01159

ELISA Type:

Cell Based

Detection Method:

Colorimetric

IHC image of PACO64881 diluted at 1:200 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG labeled by HRP and visualized using 0.05% DAB. — Choose Options

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OSTN Antibody (PACO64881)

$407

Product Code:

PACO64881

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Immunofluorescence staining of PC3 cells with PACO64877 at 1:100, counter-stained with DAPI. The cells were blocked in 10% normal Goat Serum and incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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OR9G1 Antibody (PACO64877)

$407

Product Code:

PACO64877

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Western Blot<br />
Positive WB detected in: Rat Brain tissue<br />
All lanes: Hmgb1 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 25 kDa<br />
Observed band size: 30 kDa<br /> — Choose Options

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Hmgb1 Antibody (PACO64769)

$383

Product Code:

PACO64769

Isotype:

IgG

Immunofluorescence staining of SH-SY5Y cells with PACO64941-IF at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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SEZ6 Antibody (PACO64941)

$407

Product Code:

PACO64941

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Immunofluorescence staining of Hela cells with PACO64997 at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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TTC14 Antibody (PACO64997)

$407

Product Code:

PACO64997

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Western Blot<br />
Positive WB detected in: Escherichia coli lysate<br />
All lanes: ompF antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 40 kDa<br />
Observed band size: 40 kDa<br /> — Choose Options

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ompF Antibody (PACO64865)

$407

Product Code:

PACO64865

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Immunofluorescence staining of A549 cells with PACO64597 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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ANKEF1 Antibody (PACO64597)

$407

Product Code:

PACO64597

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Antibody Name:	PPP1R14C Antibody
Antibody SKU:	PACO00997
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC, IF
Recommended Dilutions:	WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:	Human, Mouse, Rat
Immunogen:	synthesized peptide derived from the Internal region of human KEPI.

Form:	Liquid
Storage Buffer:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

UniProt Protein Function:	KEPI: Inhibitor of PPP1CA. Has over 600-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. Belongs to the PP1 inhibitor family.
UniProt Protein Details:	Protein type:Inhibitor; Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: 6q24.3-q25.3 Cellular Component: cytoplasm; membrane Molecular Function:type 1 serine/threonine specific protein phosphatase inhibitor activity Biological Process: negative regulation of catalytic activity; regulation of phosphorylation
NCBI Summary:	The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied by OMIM, Feb 2010]
UniProt Code:	Q8TAE6
NCBI GenInfo Identifier:	90110047
NCBI Gene ID:	81706
NCBI Accession:	Q8TAE6.3
UniProt Secondary Accession:	Q8TAE6,Q5VY83, Q96BB1, Q9H277,
UniProt Related Accession:	Q8TAE6
Molecular Weight:	17,843 Da
NCBI Full Name:	Protein phosphatase 1 regulatory subunit 14C
NCBI Synonym Full Names:	protein phosphatase 1 regulatory inhibitor subunit 14C
NCBI Official Symbol:	PPP1R14C
NCBI Official Synonym Symbols:	KEPI; NY-BR-81; CPI17-like
NCBI Protein Information:	protein phosphatase 1 regulatory subunit 14C
UniProt Protein Name:	Protein phosphatase 1 regulatory subunit 14C
UniProt Synonym Protein Names:	Kinase-enhanced PP1 inhibitor; PKC-potentiated PP1 inhibitory protein; Serologically defined breast cancer antigen NY-BR-81
Protein Family:	Protein phosphatase 1 regulatory
UniProt Gene Name:	PPP1R14C
UniProt Entry Name:	PP14C_HUMAN

PPP1R14C Antibody (PACO00997)

Description

PPP1R14C Antibody (PACO00997)

Overview

Properties

Additional Information

Related Products

PPP1R14C Antibody (PACO00997)

Description

PPP1R14C Antibody (PACO00997)

Overview

Properties

Additional Information

Related Products

Related Products

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