The PPP1R13L Polyclonal Antibody (CAB10462) is a valuable tool for research involving the protein PPP1R13L, which plays a role in cell cycle regulation and apoptosis. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PPP1R13L protein, this antibody enables the detection and analysis of PPP1R13L in various cell types, making it ideal for studies in cell biology and cancer research.
PPP1R13L, also known as iASPP, is a critical regulator of cell proliferation and survival, with implications in cancer progression and therapy resistance. Its involvement in apoptosis signaling pathways makes it a potential target for therapeutic intervention in cancer treatment. Understanding the function of PPP1R13L is essential for developing strategies to manipulate cell fate and enhance cancer treatment outcomes.
Product Name:
PPP1R13L Rabbit Polyclonal Antibody
SKU:
CAB10462
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 589-828 of human PPP1R13L (NP_006654.2).
IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.
Purification Method:
Affinity purification
Gene ID:
10848
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PPP1R13L antibody (CAB10462) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
