PPP1R12B Rabbit Polyclonal Antibody (CAB17510)
- SKU:
- CAB17510
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PPP1R12B Rabbit Polyclonal Antibody |
SKU: | CAB17510 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-930 of human PPP1R12B (NP_002472.2). |
Sequence: | TFSR SRAE RQAQ EQPR EKPT DTEG LEGS PEKH EPSA VPAT EAGE GQQP WGRS LDEE PICH RLRC PAQP DKPT TPAS PSTS RPSL YTSS HLLW TNRF SVPD SESS ETTT NTTT AKEM DKNE NEEA DLDE QSSK RLSI RERR RPKE RRRG TGIN FWTK DEDE TDGS EEVK ETWH ERLS RLES GGSN PTTS DSYG DRAS ARAR REAR EARL ATLT SRVE EDSN RDYK KLYE SALT ENQK LKTK LQEA QLEL ADIK SKLE KVAQ QKQE KTSD RSS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MYPT2; PP1bp55; PPP1R12B |
Positive Sample: | 293T,U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | A band, cytoplasm, cytoskeleton, cytosol, nucleoplasm, Z disc |
Calculated MW: | 110kDa |
Observed MW: | 110kDa |
Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.
Purification Method: | Affinity purification |
Gene ID: | 4660 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |