The PPP1R11 Polyclonal Antibody (PAC013572) is a valuable tool for researchers studying PPP1R11, a protein phosphatase regulator involved in cell cycle progression and tumor suppression. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards PPP1R11 in human samples, making it suitable for Western blotting applications. By binding to PPP1R11, this antibody enables precise detection and analysis of this important protein in various cellular contexts, making it an ideal choice for studies in cancer biology and cell cycle regulation.PPP1R11, also known as inhibitor-3, is a key player in regulating the activity of protein phosphatase 1 (PP1), a critical enzyme involved in numerous cellular processes.
Dysregulation of PPP1R11 has been linked to cancer development and progression, highlighting its potential as a therapeutic target in oncology research. Investigating the function of PPP1R11 can provide valuable insights into the mechanisms underlying tumorigenesis and identify novel strategies for cancer treatment and prevention. With its specificity and reliability, the PPP1R11 Polyclonal Antibody is a valuable asset for researchers aiming to explore the role of PPP1R11 in health and disease.
protein phosphatase 1, regulatory (inhibitor) subunit 11;PPP1R11;HCG-V;HCGV;MGC125741;MGC125742;MGC125743;TCTE5;TCTEX5 ;
UniProt Protein Function:
PPP1R11: Inhibitor of protein phosphatase 1.Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunitChromosomal Location of Human Ortholog: 6p22.1Cellular Component: cytoplasm; nucleus; protein phosphatase type 1 complexMolecular Function: protein binding; protein phosphatase 1 binding; type 1 serine/threonine specific protein phosphatase inhibitor activityBiological Process: negative regulation of phosphoprotein phosphatase activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex class I region on chromosome 6. [provided by RefSeq, Jul 2008]
