The PPP1CC Polyclonal Antibody is a vital tool for researchers studying PPP1CC, a crucial enzyme involved in cell division and cell cycle control. This antibody is produced in rabbits and exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications. By targeting the PPP1CC protein, this antibody enables precise detection and analysis in various cell types, making it an essential component in studies related to cell biology and cancer research.PPP1CC, also known as protein phosphatase 1 catalytic subunit gamma, plays a significant role in regulating key cellular processes such as DNA replication, cell growth, and apoptosis.
Dysregulation of PPP1CC has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting the importance of understanding its function and activity in different pathological conditions. Researchers can utilize this antibody to investigate the role of PPP1CC in disease development and to explore potential therapeutic interventions targeting this enzyme.
Product Name:
PPP1CC Polyclonal Antibody
SKU:
CAB21818
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human PPP1CC (NP_002701.1).
The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5501
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells using PPP1CC Rabbit pAb(CAB21818) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.