The PPP1CB Polyclonal Antibody (CAB13528) is a valuable tool for researchers studying PPP1CB, a key regulatory enzyme involved in cellular processes such as cell division and signal transduction. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the PPP1CB protein, the antibody allows for precise detection and analysis in a variety of cell types, making it ideal for studies in biochemistry, cell biology, and cancer research.
PPP1CB, also known as protein phosphatase 1 catalytic subunit beta, is a critical player in the regulation of key cellular pathways, including cell cycle progression and gene expression. Dysregulation of PPP1CB has been implicated in various diseases, including cancer and neurological disorders, highlighting its importance as a therapeutic target. Investigating the role of PPP1CB in these conditions is essential for uncovering new insights into disease mechanisms and developing targeted treatments to improve patient outcomes.
Product Name:
PP1 beta Rabbit Polyclonal Antibody
SKU:
CAB13528
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 227-327 of human PP1 beta (NP_002700.1).
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
5500
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PP1 beta Rabbit pAb (CAB13528) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
