The PPP1CB Polyclonal Antibody (CAB1088) is a valuable tool for researchers studying the PPP1CB protein, a key regulator of cell division and cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to PPP1CB, this antibody allows for detection and analysis of the protein in various cell types, making it ideal for studies in cell biology and cancer research.PPP1CB, a catalytic subunit of protein phosphatase 1, plays a crucial role in cell cycle progression, DNA replication, and cellular signaling pathways.
Dysregulation of PPP1CB has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. Understanding the functions and mechanisms of PPP1CB is essential for developing targeted therapies and interventions for these conditions.Overall, the PPP1CB Polyclonal Antibody (CAB1088) serves as a valuable tool for researchers exploring the roles and implications of PPP1CB in cellular processes and disease pathogenesis. Its high reactivity and specificity make it a reliable reagent for investigating the functions and regulatory mechanisms of PPP1CB in various research settings.
Product Name:
PP1 beta Rabbit Polyclonal Antibody
SKU:
CAB1088
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 227-327 of human PP1 beta (NP_002700.1).
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
5500
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PP1 beta Rabbit pAb (CAB1088) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
