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PPP1CA Monoclonal Antibody [P4G3AT] (CPAB0159)

SKU:
CPAB0159
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
P4G3AT
Applications:
WB
ELISA
€149
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Description

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PPP1CA Monoclonal Antibody [P4G3AT] (CPAB0159)

The PPP1CA Polyclonal Antibody (CPAB0159) is a powerful tool for researchers studying PPP1CA, a key enzyme involved in cellular processes such as cell division and signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been extensively validated for Western blot applications. By specifically binding to PPP1CA, researchers can detect and analyze the protein in a variety of cell types, making it an essential tool for studies in cell biology and cancer research.

PPP1CA, also known as protein phosphatase 1 catalytic subunit alpha, plays a crucial role in regulating various cellular functions by dephosphorylating key proteins. Dysregulation of PPP1CA activity has been linked to diseases such as cancer, neurodegenerative disorders, and metabolic conditions. Investigating the function of PPP1CA using this antibody is essential for gaining insights into the molecular mechanisms underlying these diseases and potentially identifying new therapeutic targets.

Product Name:PPP1CA Antibody
Product Sku:CPAB0159
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PPP1CA mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PPP1CA amino acids 3-299 purified from Ecoli.
Clone:P4G3AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:PPP1CA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:PPP1CA is one of the 3 catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase which is involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity is detected in the end stage of heart failure. Studies in both human and mice suggest that PP1 is a significant regulator of cardiac function. Mouse studies also propose that PP1 functions as a suppressor of learning and memory.
Synonyms:Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A, PPP1CA, PPP1A, protein phosphatase 1 catalytic subunit alpha isozyme, MGC1674, MGC15877, PP1alpha.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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