PPOX Rabbit Polyclonal Antibody (CAB6397)
- SKU:
- CAB6397
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PPOX Rabbit Polyclonal Antibody |
SKU: | CAB6397 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PPOX (NP_001116236.1). |
Sequence: | MGRT VVVL GGGI SGLA ASYH LSRA PCPP KVVL VESS ERLG GWIR SVRG PNGA IFEL GPRG IRPA GALG ARTL LLVS ELGL DSEV LPVR GDHP AAQN RFLY VGGA LHAL PTGL RGLL RPSP PFSK PLFW AGLR ELTK PRGK EPDE TVHS FAQR RLGP EVAS LAMD SLCR GVFA GNSR ELSI RSCF PSLF QAEQ THRS ILLG LLLG AGRT PQPD SALI RQAL AERW SQWS LRGG LEML PQAL ETHL TSRG VSVL RGQP VCGL SLQA EGRW KVSL RDSS LEAD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | VP; PPO; V290M; PPOX |
Positive Sample: | HepG2,Mouse spleen,Mouse liver,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein. |
Calculated MW: | 51kDa |
Observed MW: | 51kDa |
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method: | Affinity purification |
Gene ID: | 5498 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |