The PPME1 Polyclonal Antibody (CAB13094) is a valuable tool for researchers studying PPME1, a protein phosphatase involved in regulating cellular processes such as cell cycle progression and DNA damage response. This antibody, raised in rabbits, offers high reactivity with human samples and has been validated for Western blot applications. It specifically binds to the PPME1 protein, facilitating detection and analysis in a variety of cell types, making it an essential tool for studies in molecular biology and cancer research.
PPME1, also known as protein phosphatase methylesterase 1, is a key player in cellular signaling pathways that control cell growth and proliferation. Dysregulation of PPME1 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions. By understanding the role of PPME1 in cellular processes, researchers can gain valuable insights into disease mechanisms and potentially develop new treatments for cancer and other related conditions.
Product Name:
PPME1 Rabbit Polyclonal Antibody
SKU:
CAB13094
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human PPME1 (NP_057231.1).
This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51400
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PPME1 Rabbit pAb (CAB13094) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
