The PPM1K Polyclonal Antibody (CAB16602) is a valuable tool for researchers studying PPM1K, a protein phosphatase involved in various cellular processes such as DNA damage response and cell cycle regulation. This antibody, generated in rabbits, specifically binds to PPM1K in human samples, making it ideal for Western blot applications.PPM1K is known for its role in maintaining genome stability and regulating cell division, making it an important target for cancer research and studies on DNA repair mechanisms.
By enabling the detection and analysis of PPM1K in different cell types, this antibody allows researchers to further explore its function and potential therapeutic applications in diseases related to genomic instability.With its high reactivity and validation for Western blotting, the PPM1K Polyclonal Antibody (CAB16602) is a reliable tool for investigating the biological functions of PPM1K and its implications in cancer and other diseases associated with DNA damage and cell cycle dysregulation.
Product Name:
PPM1K Rabbit Polyclonal Antibody
SKU:
CAB16602
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 89-351 of human PPM1K (NP_689755.3).
This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.
Purification Method:
Affinity purification
Gene ID:
152926
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PPM1K Rabbit pAb (CAB16602) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.